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Esketamine spray for treating depression ‘not cost-effective’

Esketamine spray for treating depression ‘not cost-effective’

Health
A nasal esketamine spray for hard-to-treat depression has been rejected for use on the NHS for a second time because of uncertainty over cost.Despite a need for new treatments for adults, it is also not clear how well the drug works long term, the healthcare watchdog NICE said.Esketamine is a form of ketamine that targets a chemical linked with learning and memory.The treatment was first rejected in January by NICE.Following comments by experts and clinicians, a second consultation on the draft guidance for England and Wales has now been launched.The nasal spray, which contains esketamine and is also called Spravato and made by Janssen, costs about £10,000 per course of therapy.In the US, it was approved for sale last year as a treatment for depression de...
Study: Fighting climate change is more cost-effective than cleaning up the mess

Study: Fighting climate change is more cost-effective than cleaning up the mess

Science
Sept. 20 (UPI) -- It pays to fight climate change, new research suggests. Transitioning from fossil fuels to renewable energy sources won't be cheap or easy. But new research suggests the investments will pay off in the long run. That's because the cost of inaction -- letting climate change run its course and dealing with the consequences -- will be much more expensive than curbing emissions. In other words, climate mitigation efforts yield a good return on investment, researchers said. "That investment is even more compelling given the wealth of evidence that the impacts of climate change are happening faster and more extensively than projected even just a few years ago," Ove Hoegh-Guldberg, deputy director of the Australian Research Council Centre for Excellence in Coral Reef Studies,...