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Tag: drugs

FDA looks to make more prescription drugs available over the counter

FDA looks to make more prescription drugs available over the counter

Health
July 17 (UPI) -- The U.S. Food and Drug Administration wants to simplify the process of making some prescription drugs available over the counter and without physician approval. The FDA on Tuesday released draft guidelines on how a streamlined process could be beneficial for consumers, and could lead to savings on drug and care costs. The FDA specifically noted cholesterol-lowering drugs and the prescription drug naloxone, an opioid-overdose antidote, as good candidates to make available over the counter. In many states, the antidote Narcan already does not need a prescription. "Our hope is that the steps we're taking to advance this new, more modern framework will contribute to lower costs for our healthcare system overall and provide greater efficiency and empowerment for consumers by ...
Drugs carried in cellular 'backpacks' help destroy solid tumors in mice

Drugs carried in cellular 'backpacks' help destroy solid tumors in mice

Health
July 10 (UPI) -- Nanoparticle "backpacks" with immune-stimulating drugs successfully helped T cells destroy solid tumors in mice, researchers report. Engineers at the Massachusetts Institute of Technology who developed the method found it could enhance the T cells' activity without harmful side effects. In a study published Monday in the journal Nature Biotechnology, the researchers report that 60 percent of treated animals' tumors disappeared completely in an early test of the method. The drugs are made of a gel from molecules of cytokine IL-15 held together by a cross-linker that degrades when the T cell reaches a tumor and is activated. Nanoparticles are between 1 and 100 nanometers in size -- comparatively, a human hair is 75,000 nanometers thick. "We found you could greatly improve ...
Anticonvulsant drugs ineffective for back pain, can be harmful

Anticonvulsant drugs ineffective for back pain, can be harmful

Health
July 3 (UPI) -- Anticonvulsant drugs that are commonly prescribed to treat back pain are not effective and might be harmful, according to a new study. Researchers led by the University of Sydney analyzed nine placebo-controlled randomized trials that showed a lack of benefit from anticonvulsants, also known as gabapentinoids, and that they could instead cause adverse reactions. The findings were published Monday in the Canadian Medical Association Journal. "We have shown, with mostly high-and moderate-quality evidence, that common anticonvulsants are ineffective for chronic low back pain and lumbar radicular pain and are accompanied by increased risk of adverse events such as drowsiness or dizziness," Christine Lin, an associate professor at the University of Sydney, said in a press rele...
No drugs test for at least a quarter of EFL players in 2016-17

No drugs test for at least a quarter of EFL players in 2016-17

Sports
At least a quarter of players who appeared in the English Football League last season were not drugs tested by UK Anti-Doping (Ukad), despite a rise in testing across England's top divisions.Ukad collected 1,494 samples from 2,047 EFL players in 2016-17, leaving a minimum of 553 players untested.One player being tested twice would account for two samples.Professor Ivan Waddington, an expert in doping in sport, described the level of testing in the EFL as "unacceptable".Ukad does not disclose how many players were tested multiple times, meaning the percentage of untested players could feasibly be greater than a quarter.'I was only drugs tested once in the Premier League'What about the overall figures in England?The Football Association said it runs "one of the most comprehensive national an...
Light-activated cancer drugs may minimize chemotherapy side effects

Light-activated cancer drugs may minimize chemotherapy side effects

Health
Feb. 13 (UPI) -- Chemotherapy drugs activated by light to treat cancer can minimize side effects by targeting strictly non-healthy cells, according to new research in Britain and Australia.The Monash Warwick Alliance, an intercontinental collaboration between the University of Warwick in Britain and Monash University in Australia, examined how a platinum-based chemotherapy drug candidate kills cancer cells in targeted areas after being activated by light -- but can be directed away from healthy tissue.'"The current shortcomings of most chemotherapeutic agents are unfortunately undeniable, and therefore there is ongoing effort to develop new therapies and improve our understanding of how these agents work in effort to develop not only more effective, but also more selective, therapies to re...