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Esketamine spray for treating depression ‘not cost-effective’

Esketamine spray for treating depression ‘not cost-effective’

Health
A nasal esketamine spray for hard-to-treat depression has been rejected for use on the NHS for a second time because of uncertainty over cost.Despite a need for new treatments for adults, it is also not clear how well the drug works long term, the healthcare watchdog NICE said.Esketamine is a form of ketamine that targets a chemical linked with learning and memory.The treatment was first rejected in January by NICE.Following comments by experts and clinicians, a second consultation on the draft guidance for England and Wales has now been launched.The nasal spray, which contains esketamine and is also called Spravato and made by Janssen, costs about £10,000 per course of therapy.In the US, it was approved for sale last year as a treatment for depression de...