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Tag: Gene

Gene editing of British produce could hamper exports to the EU

Gene editing of British produce could hamper exports to the EU

Technology
The body representing food and drink manufacturing in the UK warns there could be "barriers" to exporting English farmed foods if gene editing is allowed. The government has launched a consultation on whether to green light the process, which it says could allow farmers to grow crops that perform better and reduce impact on the environment. The process is highly restricted in the EU, after the European Court of Justice ruled in 2018 that gene editing must come under the same strict rules as genetic modification.The Food and Drinks Federation (FDF) has welcomed the consultation - but told Sky News if gene editing is allowed in England, it could create hurdles for farmers exporting goods to the EU.Helen Munday, chief scientific officer of the FDF, said: "We feel positive there are some ...
Circadian gene mutations linked to increased risk for substance abuse in study with mice

Circadian gene mutations linked to increased risk for substance abuse in study with mice

Science
Dec. 2 (UPI) -- Mice trained to self-administer cocaine went on more benders when they carried a mutation in the NPAS2 gene, a gene that regulates circadian rhythms. The research, published Wednesday in the Journal of Neuroscience, suggests a link between the disruption of wake-sleep cycles and substance abuse. Advertisement Circadian genes are found in nearly every cell in the brain and body, but some circadian genes are unique to specific parts of the brain. NPAS2 is highly expressed in the forebrain, specifically the striatum and nucleus accumbens, which helps operate the brain's reward system. "This suggests that NPAS2 might play a particularly important role in regulating rhythms in these brains regions, which is part of the appeal of studying NPAS2 and rewards," lead study author L...
Gene editing method may cause chromosome loss in developing embryos

Gene editing method may cause chromosome loss in developing embryos

Health
Oct. 29 (UPI) -- Researchers testing technology to edit DNA during human development -- with the hope of preventing disease -- have found that the process often eliminates an entire section of genetic material and could threaten the health of the baby, according to a study published Thursday in the journal Cell. The technology, the CRISPR/Cas9 genome editing method, allows scientists to make precise changes to the DNA of cells. Advertisement Chromosomes are DNA molecules that carry genetic information from parent to child, and they exist in matching pairs, with one for each pair inherited from each biological parent. This chromosome loss, the result of a "single break" in embryonic DNA during the editing process, could have a significant impact on the healthy development of the baby, the ...
Study: One-third of prostate cancer tumors in Black men have dangerous gene mutations

Study: One-third of prostate cancer tumors in Black men have dangerous gene mutations

Health
Oct. 28 (UPI) -- More than one-third of Black men with prostate cancer carry potentially dangerous genetic mutations that cause more severe disease, an analysis published Wednesday by the journal Molecular Cancer Research found. Researchers sequenced 39 genes of interest in prostate cancer tumors and matched normal tissue from 77 Black-American men with prostate cancer, finding that roughly 35% of patients' tumors harbored potentially damaging mutations in several genes. Advertisement "Our research suggests that there may be key genetic differences in the prostate tumors of individuals who belong to different race groups," study co-author Jianfeng Xu told UPI. "This could impact the way their cancer progresses and the treatment options available to them." "And we found that certain mutati...
Gene editing to produce ‘super dad’ livestock

Gene editing to produce ‘super dad’ livestock

Science
Scientists have produced gene-edited animals they say could serve as "super dads" or "surrogate sires".The pigs, goats, cattle and mice make sperm carrying the genetic material of donor animals.The researchers used a hi-tech gene editing tool to knock out a male fertility gene in animal embryos.The animals were born sterile, but began producing sperm after an injection of sperm-producing cells from donor animals.The technique would enable surrogate males to sire offspring carrying the genetic material of valuable elite animals such as prize bulls, said a US-UK team.This would be a step towards genetically enhancing livestock to improve food production, they added.Prof Jon Oatley, of Washington State University's College of Veteri...