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Tag: Genetic

Genetic changes in blood may predict leukemia diagnosis

Genetic changes in blood may predict leukemia diagnosis

Health
July 9 (UPI) -- Studying genetic changes in blood, researchers have found a way to identify people at high risk of developing acute myeloid leukemia several years before diagnosis. In the study, published Monday in the journal Nature, researchers from around the world found changes in DNA can reveal the roots of AML in healthy people an average of 6.3 years before symptoms. The researchers hope that methods of reducing the likelihood of developing the cancer will arise with earlier detection and monitoring of those at risk of AML. "Acute myeloid leukemia often appears very suddenly in patients, so we were surprised to discover that its origins are generally detectable more than five years before the disease develops," first author Dr Grace Collord, of the Wellcome Sanger Institute and Un...
Genetic secrets of the rose revealed

Genetic secrets of the rose revealed

Science
Take time to smell the roses, the saying goes, and, according to scientists, the fragrant flowers could smell even sweeter in the future.For the first time researchers have deciphered the full genetic "book" of this most prized of plants.The secret history of the rose reveals surprises - it is more closely related to the strawberry than we thought.And in the long term the work could lead to roses with new scents and colours, says an international team.The new genome map, which took eight years to complete, reveals genes involved in scent production, colour and the longevity of flowers, said Mohammed Bendahmane of ENS de Lyon, in Lyon, France, who led the research."You have here a book of the history of the rose," he told BBC News. "A book that helps us understand the rose, its history and ...
Dozens of genetic risk factors found for depression

Dozens of genetic risk factors found for depression

Technology
A major new study which has identified 44 genetic risk factors for depression has the "potential to revitalise treatment", scientists have said. The international study, co-led by King's College London, is the largest carried out into a genetic basis for depression and involved more than 200 scientists.Seven data sets were combined, covering 130,000 sufferers.Among the 44 genetic variants identified, 30 are newly discovered.Previous studies have struggled to identify more than a handful. A significant number were linked to the targets of current antidepressant medications.Researchers said that all humans carry some of the 44 risk factors, and that the genetic basis for depression is shared with other psychiatric disorders such as schizophrenia.A higher body mass index is also linked to an ...
Genetic score can identify infants at risk for type 1 diabetes

Genetic score can identify infants at risk for type 1 diabetes

Health
April 2 (UPI) -- Researchers have developed a genetics score that can identify infants at risk for type 1 diabetes, according to a new study.The scientists calculated genetic scores from more than 30 genes among 3,498 children with no family history of type 1 diabetes but with gene variants known to convey type 1 diabetes risk. Their findings were published Tuesday in PLOS Medicine.In type 1 diabetes, the pancreas isn't making insulin or is making very little of the hormone. Insulin enables blood sugar to enter the cells in the body and be converted for use as energy. To make up for the insulin, type 1 diabetics need insulin shots or an insulin pump.It's usually diagnosed in children, teens and young adults, but it can develop at any age, according to the Centers for Disease Control and Pr...
Hospitals 'failing' on genetic bowel cancer test

Hospitals 'failing' on genetic bowel cancer test

Health
More than 80% of NHS hospitals in England are failing to test bowel cancer patients for the genetic condition Lynch syndrome, according to the charity Bowel Cancer UK.The condition increases the risk of bowel and other cancers. Bowel Cancer UK estimates that 166,000 people in the UK are unaware that they have the condition.An NHS England spokeswoman said there are clear guidelines about when it is appropriate to test for Lynch syndrome. Testing for the syndrome can guide the treatment of the patient and indicates whether their families are at risk. Children of people with the condition have a 50/50 chance of developing it.The charity says it is important to find out whether patients have Lynch syndrome, because some chemotherapy drugs are ineffective for them.And if other family members fi...