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Miniature human brain implants survive, grow inside mice for months

Miniature human brain implants survive, grow inside mice for months

Science
April 16 (UPI) -- Miniature human brains, or human brain organoids, can survive and grow after being implanted in the skulls of mice. It's the first time human cerebral organoids have been installed inside another species.Researchers describe the breakthrough in a new paper published Monday in the journal Nature Biotechnology.Scientists grew the pea-sized brains from stem cells and then placed them inside the skulls of mice. Researchers removed a small amount of tissue to make room for the miniature brains. Tiny, transparent windows in the skulls of the test mice allowed scientists to keep tabs on the brain implants -- the organoids were also designed to express a green fluorescent protein, causing them to glow inside the mice skulls.Roughly 80 percent of the implants were successfully rec...