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Tag: opioids

FDA approved opioids for chronic pain despite lacking ‘critical’ safety data, analysis finds

FDA approved opioids for chronic pain despite lacking ‘critical’ safety data, analysis finds

Health
Sept. 28 (UPI) -- The U.S. Food and Drug Administration approved nearly 50 new prescription opioid pain medications between 1997 and 2018, even though it lacked "critical" data on safety and effectiveness, an analysis published Monday by the journal Annals of Internal Medicine found. None of the 48 drugs granted agency approval during the more than 20-year period was evaluated in clinical trials that lasted longer than 12 weeks, and the trials often included narrowly defined groups of patients, researchers said. Advertisement And few included "systematic assessments" of risks associated with these medications, including addiction potential and non-medical use. "Our analysis provides a window through which to view the FDA's opioid regulation over the past 20 years," study co-author Dr. Cal...
Rwanda avoids US-style opioids crisis by making own morphine

Rwanda avoids US-style opioids crisis by making own morphine

Health
BUSHEKELI, Rwanda -- It was something, the silence. Nothing but the puff of her breath and the scuff of her slip-on shoes as Madeleine Mukantagara walked through the fields to her first patient of the day. Piercing cries once echoed down the hill to the road below. What she carried in her bag had calmed them. For 15 years, her patient Vestine Uwizeyimana had been in unrelenting pain as disease wore away her spine. She could no longer walk and could barely turn over in bed. Her life narrowed to a small, dark room with a dirt-floor in rural Rwanda, prayer beads hanging on the wall by her side. A year ago, relief came in the form of liquid morphine, locally produced as part of Rwanda’s groundbreaking effort to address one of the world’s great inequities: As thousands die from addiction in ri...

Settlement money won’t restore Ohio city upended by opioids

Health
The tentative settlement involving the opioid crisis and the maker of OxyContin could mean that thousands of local governments will one day be paid back for some of the costs of responding to the epidemic. But for public officials in Akron, no amount of money will restore the families and institutions that were upended by prescription painkillers, heroin and fentanyl. "The overwhelming sense of hopelessness that took over this community in 2016, you can't monetize that," former Assistant Summit County Prosecutor Greta Johnson told lawyers in a deposition in January. "Every single day the newspaper was reporting on the overdose death rates. You could not go into a community setting where there were not weeping mothers talking about their children." OxyContin maker Purdue Pharma struck a pr...
Doctors more likely to prescribe opioids at late-day appointments, study says

Doctors more likely to prescribe opioids at late-day appointments, study says

Health
Aug. 30 (UPI) -- Doctors who run late or schedule late-day appointments are more likely to prescribe opioids to patients, a discovery that might be unexpectedly contributing to the opioid epidemic, a new study says. A patient is 33 percent more likely to receive a prescription during a late-day doctor's appointment than one earlier in the day, according to a findings published Friday in Jama Open Network. They're also 17 percent more likely to receive an opioid prescription if their doctor is running at least an hour late compared to being less than 10 minutes late. "Physicians play a pivotal role in the opioid epidemic and it's important to understand what factors drive opioid prescribing," Hannah Neprash, a researcher at the University of Minnesota and study corresponding author, told ...