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New drug shows promise for pneumonia caused by COVID-19, study finds

New drug shows promise for pneumonia caused by COVID-19, study finds

Health
April 6 (UPI) -- Researchers may have identified a new drug that can reduce the lung damage associated with COVID-19. The antiviral EIDD-2801 was effective in mice at preventing severe pneumonia caused by the new coronavirus, which has likely been a key driver of serious disease and death in some of those infected, according to findings published Monday in the journal Science Translation Medicine. The drug has now finished testing in mice and will begin human clinical trials later this spring, the authors said. "This new drug not only has high potential for treating COVID-19 patients, but also appears effective for the treatment of other serious coronavirus infections," co-author Ralph Baric, professor of epidemiology at UNC-Chapel Hill Gillings School of Global Public Health, said in s...
Plasma transfusion shows promise for COVID-19 treatment, says China study

Plasma transfusion shows promise for COVID-19 treatment, says China study

Health
March 27 (UPI) -- Donor blood plasma from people who have recovered from COVID-19 appears to work as a treatment for the virus, a new analysis has revealed. Published Friday by JAMA, the study involving five patients from Shenzhen, China, treated with the approach saw many of their symptoms resolves within several days. It's believed that the blood of those who recover from the infection may contain elevated levels of antibodies that can be used to bolster the immune systems of patients with the disease. The approach has been tried with other serious infectious diseases, including Ebola and SARS, another coronavirus. New York earlier this week announced plans to start a trial of the treatment in patients diagnosed with COVID-19 in the state. The Manhattan-based New York Blood Center has ...
Study: Cognitive ability is a whole-brain phenomenon

Study: Cognitive ability is a whole-brain phenomenon

Science
March 27 (UPI) -- New research suggests intelligence, or general cognitive ability, can't be traced to a single region of the brain. According to an international team of neuroscientists, cognitive intelligence is a whole-brain phenomenon. For the study, researchers used diffusion tensor imaging to study whether small variations in the the neural wiring systems of test subjects could account for differences in IQ. The international survey involved the brain scans and IQ tests of 1,717 participants from all over the world, including healthy subjects and patients with schizophrenia. Scientists at the National University of Ireland Galway used novel statistical methods to synchronize and analyze the data collected by participating researchers. "To date, this is the largest meta-analysis stu...
Mammal study explains ‘why females live longer’

Mammal study explains ‘why females live longer’

Science
A new study that looks at lifespan in wild mammals shows that females live substantially longer than males.The research finds that, on average, females live 18.6% longer than males from the same species.This is much larger than the well-studied difference between men and women, which is around 8%.The scientists say the differences in these other mammals are due to a combination of sex-specific traits and local environmental factors.In every human population, women live longer than men, so much so that nine out of 10 people who live to be 110 years old are female. This pattern, researchers say, has been consistent since the first accurate birth records became available in the 18th Century. While the same assumption has been held ...
Stickleback study shows epigenetic changes key to climate change adaptation

Stickleback study shows epigenetic changes key to climate change adaptation

Science
March 23 (UPI) -- Epigenetic changes, not beneficial genetic mutations, are the best hope for species as they adapt to climate change. In a new study, scientists used a fish model from the Baltic Sea, the three-spined stickleback, to observe the affects of epigenetics on adaptation. "Our experiment shows that epigenetic modifications affect adaptation, but also that the changes from one generation to the next are smaller than previously assumed," study co-author Melanie Heckwolf, biologist at the GEOMAR Helmholtz Centre for Ocean Research Kiel in Germany, said in a news release. Epigenetic changes in the DNA are biochemical changes that alter the expression of genes, causing certain genes to be turned on or off. A growing amount of evidence suggests a variety of environmental factors can...