Study: Cancer cells weakened when they're more acidic
July 31 (UPI) -- Researchers have found that cancer cells are weakened when they become less acidic, which they say shows promise for developing new ways to treat the disease. If the cells' internal pH is lowered, they proliferate less and in a less robust manner, according to researchers at the Institute for Research in Biomedicine in Barcelona, Spain. Findings from the computational model, which were done in collaboration with the Moffitt Cancer Center in Tampa, Fla., and the University of Maryland, were published Tuesday in the journal Nature Communications. "Collectively, our findings suggest that cancer cells have superior fitness at an alkaline pHi, and that their reliance on an alkaline intracellular environment confers vulnerabilities that can be exploited for therapeutics," the r...
