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‘Ice-cream toothache’ mystery explained

‘Ice-cream toothache’ mystery explained

Health
Getty ImagesScientists believe they have worked out why biting down on ice or drinking something really cold causes excruciating pain for some people. They have located the cells and signals in sensitive teeth that detect big temperature drops and trigger toothache and brain jolt. People with dental decay are prone to it because the pathway is exposed.It provides a target for new treatments, such as toothpastes, dental patches or chewing gum, they say.Prof Katharina Zimmermann is lead investigator of the work, published in the journal Science Advances. "Once you have a molecule to target, there is a possibility of treatment," she explained.The target is called TRPC5, and Prof Zimmermann's team at the Friedrich-Alexander University Erlangen-Nürnberg in Germany traced its location to a speci...