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Esketamine spray for treating depression ‘not cost-effective’

Esketamine spray for treating depression ‘not cost-effective’

Health
A nasal esketamine spray for hard-to-treat depression has been rejected for use on the NHS for a second time because of uncertainty over cost.Despite a need for new treatments for adults, it is also not clear how well the drug works long term, the healthcare watchdog NICE said.Esketamine is a form of ketamine that targets a chemical linked with learning and memory.The treatment was first rejected in January by NICE.Following comments by experts and clinicians, a second consultation on the draft guidance for England and Wales has now been launched.The nasal spray, which contains esketamine and is also called Spravato and made by Janssen, costs about £10,000 per course of therapy.In the US, it was approved for sale last year as a treatment for depression de...
Dow futures rip 700 points higher amid report Gilead drug showing effectiveness treating coronavirus

Dow futures rip 700 points higher amid report Gilead drug showing effectiveness treating coronavirus

Finance
U.S. stock futures surged on Thursday night after a report said a Gilead Sciences drug was showing effectiveness in treating the coronavirus. The move pointed to a jump for the stock market on Friday.Dow Jones Industrial Average futures were up 700 points, or about 3%. S&P 500 futures gained 2.8% while Nasdaq 100 futures were up by 1.8%.Gilead shares jumped by 14% in after-hours trading after STAT news reported that a Chicago hospital treating coronavirus patients with Remdesivir in a trial were recovering rapidly from severe symptoms. The publication cited a video it obtained where the trial results were discussed."This is obviously good news. Of course, we've heard a few other pieces of good news like this recently and they didn't pan-out as well as people had hoped," said ...
Blackpool owners, the Oyston family, accused of treating club as ‘personal cash machine’ by High Court

Blackpool owners, the Oyston family, accused of treating club as ‘personal cash machine’ by High Court

Sports
The owners of Blackpool, the Oyston family, have been accused at the High Court of treating the football club as "the family's personal cash machine".Lawyers for Latvian millionaire Valeri Belokon, the club's president, were launching what could prove to be one of British football's most expensive legal actions.Andrew Green QC alleged on Monday at the start of a five-week hearing that Owen and Karl Oyston, owner and chairman of the Lancashire club, had "improperly" extracted millions of pounds from its funds following promotion to the Premier League in 2010 and used the money for their own benefit.Belokon's company VB Football Assets, a minor shareholder in the club, was excluded from key decisions, information and any share of profits, said Green.VB Football is pursing a claim against the...