
Study could make pancreatic cancer treatments more personalized
June 29 (UPI) -- A new study published this week in Immunity could change the way oncologists tailor treatments to a patient's specific type of tumor. A team of scientists at Penn Medicine's Abramson Cancer Center looked at why tumors with more T cells, or cells that play a vital role in the immune response, are more sensitive to immunotherapy than those with fewer T cells. Those with more of these cells are known as "hot" tumors and those with less are known as "cold." The researchers looked at the role of "tumor heterogeneity," a cancer cell's ability to move, replicate, metastasize and respond to treatment. They found that whether a tumor is hot or cold is determined by information embedded in the cancer cells themselves. Recent findings from Penn Medicine and other institutions have ...