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Tag: selfrepair

Spinal disk cells in zebrafish can self-repair

Spinal disk cells in zebrafish can self-repair

Science
June 22 (UPI) -- The cells that make up the developing backbone of zebrafish can self-repair, new research shows. Unfortunately these cells disappear as the backbone matures.Before developing a backbone, embryonic and newly hatched zebrafish are supported by a notochord -- a proto-spine. The soft spine structure is similar to a water-filled garden hose. A shell of epithelial cells protects fluid-filled cells called vacuolated cells.Previous studies suggest tiny sacs in the membranes of vacuolated cells, called caveolae, prevent the fluid cells from popping as the young fish begin swimming.Researchers engineered zebrafish to be without caveolae, to see whether the tiny sacs are essential to spinal chord health and development."In the caveolar mutants, you see these serial lesions up and dow...